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. 2015 Mar 23;7(3):1429–1453. doi: 10.3390/v7031429

Figure 4.

Figure 4

Fas-associated death domain (FADD) and IL-28B co-delivery improved cell-mediated immune (CMI) responses for SIVmac Gag. C57BL/6 mice were immunized with 2 μg plasmid pJ603-gag combined with 2 μg plasmid pJ603-cFLIP or plasmid IL-28B or 4 μg plasmid pJ603-FADD at day 0 and day 28. Mice were euthanized 10 (A) or 36 (B and C) days after the last immunization and splenocytes were prepared for cellular immune response assay; Data in A–C are representative of two independent experiments with similar results (n=5 except for control group where n=4). pcDNA3.1 was added to make sure all the vaccinated mice received the same quantity of plasmids.