Table 6.
A list of filtered DDI-ADE pairs for the drug “Simvastatin” classified by CTCAE grades
| CTCAE grade | AERS outome code | Drug code by RxCUI | Drug name | Drug code by RxCUI | Drug name | ADE code by MedDRA | ADE name |
|---|---|---|---|---|---|---|---|
| Grede 5 | DE | 36567 | Simvastatin | 1191 | Aspirin | 10002906 | Aortic stenosis |
| Grede 5 | DE | 253198 | Risiglitazone maleate | 36567 | Simvastatin | 10006580 | Bundle branch block left |
| Grede 5 | DE | 36567 | Simvastatin | 203160 | Losartan Potassium | 10007515 | Cardiac arrest |
| Grede 5 | DE | 36567 | Simvastatin | 1191 | Aspirin | 10010071 | Coma |
| Grede 5 | DE | 253198 | Risiglitazone maleate | 36567 | Simvastatin | 10012689 | Diabetic retinoathy |
| Grede 4 | LT | 36567 | Simvastatin | 203029 | Tegretol | 10002948 | Aphasia |
| Grede 4 | LT | 36567 | Simvastatin | 203029 | Tegretol | 10003119 | Arrhythmia |
| Grede 4 | LT | 253198 | Amiodarone hydrochloride | 316675 | Simvastatin 80 MG | 10006002 | Bone pain |
| Grede 4 | LT | 36567 | Simvastatin | 225807 | exelon | 10007515 | Cardiac arrest |
| Grede 4 | LT | 36567 | Simvastatin | 203029 | Tegretol | 10012455 | Dematitis exfoliative |
| Grede 3 | DS | 36567 | Simvastatin | 1191 | Aspirin | 10012455 | Dematitis exfoliative |
| Grede 3 | DS | 36567 | Simvastatin | 190465 | Viagra | 10018429 | Glucose tolerance impaired |
| Grede 3 | DS | 36567 | Simvastatin | 83367 | Atorvastatin | 10020765 | Hypersomia |
| Grede 3 | DS | 36567 | Simvastatin | 35296 | Ramipril | 10050295 | Intervertebral disc protrusion |
| Grede 3 | DS | 253198 | Gemfibrozil 600 MG | 316675 | Simvastatin 80 MG | 10000486 | Acidosis |