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Ghrelin receptors are expressed on human monocytes. (A) Human PBMCs were double stained with CD14 PE and GHS-R AF-488. (B) Immunofluorescence labeling revealed GHS-R expression on cell surface of purified monocytes (upper panel); negative control failed to show any specific staining (lower panel). Ghrelin inhibits IL-1β (C) and IL-6 (D) secretion from LPS-treated (10 ng/ml) monocytes.
