Figure 7.
Cytokine levels in the serum of treated mice after LPS and ghrelin treatment. Cytokines tested were IL-1β (A), IL-6 (B), and TNF-α (C) at 4 hours and IL-1β (D) and IL-6 (E) at 24 hours. Ghrelin stimulates food intake in LPS challenged mice (F). Ghrelin treatment inhibits basal IL-1β and IL-1α secretion in periphery (G and H). Ghrelin also inhibits serum IL-1α levels 24 hours after LPS challenge (I). Values are expressed as mean ± SEM (*P < 0.05).