Table 3.
Summary of protein expression in the developing chick choroid plexus.
| Stroma | Epithelium | |||
|---|---|---|---|---|
| E12 | E19/20 | E12 | E19/20 | |
| NEURAL STEM/PROGENITOR CELL | ||||
| Sox2 | – | nd | ✓ | nd |
| Otx2 | – | – | ✓ | ✓ |
| Vimentin* | ✓ (low) | ✓ (low) | ✓ (high) | ✓ (high) |
| Transitin | ✓ | √ | – | – |
| GFAP | ✓ | ✓ | – | – |
| Cytokeratin | - | nd | ✓ | nd |
| Doublecortin | ✓ | ✓ | – | – |
| NEURONAL | ||||
| ß3-tubulin | ✓ | ✓ | – | – |
| Neurofilament | ✓ | ✓ | – | – |
| Synaptic vesicles (SV2) | ✓ | ✓ | – | – |
| Tyrosine hydroxylase | ✓ | nd | – | nd |
| TIGHT JUNCTION PROTEINS | ||||
| ZO-1 | – | – | ✓ | ✓ |
| ASPP2 | ✓ | ✓ | ✓ | ✓ |
| Connexin-34 | – | – | ✓ | ✓ |
| OTHERS | ||||
| Laminin | ✓ | nd | – | nd |
| Aquaporin-1 | – | nd | ✓ | nd |
| Clusterin* | ✓ (low) | ✓ (low) | ✓ (high) | ✓ (high) |
–, negative; nd, not done;
*
particularly low levels of expression in the CP stroma and high levels of expression in the CP epithelium are indicated.