Figure 10.

Early visual experience does not prevent the refinement of RFs in the SC. This experiment tested the alternative hypothesis that enlarged RFs in animals that received early visual experience from P8 to 21 were caused by a failure of RFs to refine rather than a failure to maintain their refined state. Single-unit RFs were measured at P60 in animals that had visual experience from P8 to 21 preceded and followed by DR. (A) Experimental design. Conventions as in Figure 1. We found that RF width (B) and RF area (C) were not different than in P90 normal controls, refuting the alternate hypothesis that early light exposure prevented RF refinement. Data are presented as median ± IQR.