Figure 2.

Imaging results from dorsolateral prefrontal, parietal and visual cortices. Top row: voxels where BOLD activity was responding to positively correlated with mean-related uncertainty (U_Mr, in red), and positively correlated with variance-related uncertainty (U_Vr, in yellow). All activations are rendered on the template brain of the Montreal Neurological Institute with an uncorrected threshold of P < 0.001 (see text and tables for full list of activation and peak coordinates). Bottom row: average parameter estimates from a 5 mm sphere centered on the peak activation from the cluster highlighted with a dashed ellipse, for regressors encoding uncertainty due to the mean and variance for relevant and irrelevant dimensions. Stars indicate significance: *P < 0.05, **P < 0.01, ***P < 0.001. Red and yellow shading denotes the condition used to define the ROI. (a) Voxels in the inferior parietal cortex (IPL) responding to U_Mr. (b) Voxels in the dorsolateral prefrontal cortex (dlPFC) responding to U_Mr (c) superior parietal cortex (SPL) showed a positive correlation with U_vr (and U_Mr, see bar plot). (d and e) We subdivided a large region of visual cortex showing activity positively correlated with U_vr into superior (sVis) and inferior (iVis) regions.