Table 1.
Summary of lung-related structure and function 42 days after 15 Gy
| Parameters at 42 days | 0 Gy |
15 Gy |
P < 0.05 0 Gy vs 15 Gy | ||
|---|---|---|---|---|---|
| Mean ± SD | n | Mean ± SD | n | ||
| Body weight (gram) | 167 ± 7 | 13 | 140 ± 11 | 30 | yes |
| Breathing rate (breaths/minute) | 135 ± 13 | 4 | 269 ± 44 | 8 | yes |
| Arterial oxygen saturation (%) | 92 ± 3 | 4 | 75 ± 13 | 8 | yes |
| Whole lung wet weight (gram) | 0.7 ± 0.1 | 9 | 1.5 ± 0.3 | 23 | yes |
| Lung wet:dry weight | 4.4 ± 0.1 | 8 | 4.6 ± 0.2 | 15 | yes |
| Pleural effusions (milliliter) | 0 ± 0 | 15 | 2.5 ± 2.5 | 33 | yes |
| Histology score (sum of 4 categories) | 2.8 (2.1–4.4) Median (25–75%) | 4 | 7.8 (6.0–9.1) Median (25–75%) | 8 | yes |
| Right ventricular hypertrophy (RV/LV + S) | 0.23 ± 0.06 | 4 | 0.44 ± 0.08 | 8 | yes |
SD = standard deviation, R = right, L = left, V = ventricle, S = septum.