Fig. 6.

GM-CSF, IL-2, IL-5, IL-6 and IL-17 showed significant changes over the course of the experiments. WR-2721 reversed the radiation-induced changes in IL-2 and IL-6. In the PGN group, IL-5 and IL-6 levels were similar to those in the IR group. The combination of WR-2721 and PGN was unable to reverse the increase in IL-6 observed following IR (A). IL-6, IL-17 and GM-CSF in the serum of mice treated with WR-2721 and PGN were all significantly higher than in the unirradiated mice on Day 9 (B) (*P < 0.05).