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. 2015 Mar 17;2015:542026. doi: 10.1155/2015/542026

Table 3.

Semiquantitative analyses of histopathological changes of the liver.

Parameters Normal Diabetic Diabetic
250 mg/kg 
V. vinifera
500 mg/kg 
V. vinifera
600 μg/kg 
glibenclamide
Necrosis 0 ++ + + +
Sinusoidal 
hyperemia
0 ++ ++ + 0
Connective tissue inflammation in portal region 0 ++ + 0 0

0: no changes, +: mild changes, ++: moderate changes, and +++: severe changes.