Table 2. Metabolic Syndrome Case definition.
| Metabolic Syndrome Definition Source | Metabolic Syndrome Definition Criterion | Cases Identified 1 |
|---|---|---|
| Adopted National Cholesterol Education Program (NCEP) | Presence of at least THREE of the following: | 33 |
| 1. Elevated diastolic or systolic blood pressure (> 95th percentile) | ||
| 2. Overweight or obese (BMI) | ||
| 3. Elevated triglycerides (> 75th percentile) | ||
| 4. Low HDL cholesterol (<25th percentile) | ||
| 5. Elevated Glucose (> 100mg/dL) | ||
| World Health Organization (WHO) | Impaired fasting glucose (glucose > 100mg) or Insulin Resistance (HOMA-IR > 3.16) AND at least TWO of the following: | 9 |
| 1. Elevated blood pressure | ||
| 2. Overweight or Obese (BMI) | ||
| 3. Elevated triglycerides (>75th percentile) | ||
| 4. Low HDL cholesterol (<25th percentile) | ||
| International Diabetes Foundation (IDF) | Increased waist circumference (≥ 90th percentile; ethnicity specific) AND at least TWO of the following | 5 |
| 1. Raised triglycerides (≥ 150 mg/dl | ||
| 2. Reduced HDL-cholesterol (≤40mg/dL for boys, ≤ 50mg/dL for girls) | ||
| 3. Raised blood pressure (systolic ≥ 130 mm Hg, diastolic ≥85 mm Hg) | ||
| 4. Elevated fasting glucose (>100 mg/dL) | ||
| Current Metabolic Syndrome Study | Subjects that fulfill the criteria for at least ONE of the three metabolic syndrome definitions: Adopted NCEP, WHO, IDF | 37 2 |
Note: Where applicable, above definitions show adjustments from adult thresholds to better fit a pediatric cohort; for ethnicity specific thresholds, the Turkish population was used as a reference unless otherwise indicated.
1Number of metabolic syndrome cases identified according to the specified definition; subjects may fulfill the criteria for multiple definitions simultaneously.
2Number represents unique cases that fulfill the criteria presented by at least one of the following sources: Adopted NCEP, WHO, or IDF. This is the number of cases used in the present study.