Table 4.
Summary of Neurocognitive Testing.
| Control (n = 30) Mean (SD) | MDD (n = 31) Mean (SD) | Comparison Control vs. MDD | |
|---|---|---|---|
| Attention | GLM MANOVA | ||
| CPT-Identical Pairsa | n = 30 | n = 31 | F(3,57) = 3.52, p < .05 |
| CPT2 | 3.82 (.40) | 3.39 (.71) | F(1,59) = 8.38, p < .01 |
| CPT3 | 2.82 (.92) | 2.43 (.90) | F(1,59) = 2.80, p = .10 |
| CPT4 | 1.68 (.90) | 1.20 (.86) | F(1,59)= 4.55, p < .05 |
| GLM MANOVA | |||
| ANT | n = 29 | n = 31 | F(3,56) = 1.23, p = .31 |
| Alerting (RT) | 43.29 (19.28) | 42.99 (34.55) | F(1,,58) = 0.01, p = .97 |
| Orienting (RT) | 49.78 (20.16) | 55.83 (29.62) | F(1,58) = 0.84, p = .36 |
| Conflict (RT) | 92.60 (22.81) | 118.62 (69.65) | F(1,,58) = 3.68, p = .06 |
| Affective Decision Making | |||
| GLM ANOVA | |||
| IGT | n = 30 | n = 30 | F(1,57) = 3.07, p = .09b |
| Advantageous Choices | Male (n = 14): 59.5 (12.98) | Male (n = 11): 51.73 (13.37) | |
| Female (n = 16): 49.94 (8.68) | Female (n = 19): 52.26 (10.86) | ||
|
Cognitive Control of
Emotion Processing |
|||
| GLM Repeated Measures MANOVA | |||
| Emotion Go/NoGo | n = 25 | n = 31 | F(2,104) = 0.43, p = .65 |
| Fear (RT) | 485.94 (67.82) | 523.07 (82.79) | |
| Happy (RT) | 461.08 (65.96) | 493.51 (74.30) | |
| Calm (RT) | 483.02 (87.29) | 510.03 (73.67) | |
| GLM Repeated Measures MANOVA | |||
| Face Go/NoGo | |||
| Go Trials | n = 25 | n = 31 | F(3,162) = 0.13, p = .94 |
| Angry/Neutral (RT) | 336.51 (43.46) | 343.81 (58.76) | |
| Fear/Neutral (RT) | 328.55 (46.81) | 347.90 (54.03) | |
| Sad/Neutral (RT) | 362.36 (52.59) | 378.34 (48.45) | |
| Happy/Neutral (RT) | 303.71 (40.68) | 322.07 (55.0) | |
| NoGo Trials | n = 25 | n = 31 | F(3,50) = 1.36, p = .27 |
| Neutral/Angry (RT) | 345.32 (50.67) | 383.66 (67.19) | |
| Neutral/Fear (RT) | 339.22 (55.28) | 346.05 (57.14) | |
| Neutral/Sad (RT) | 368.61 (61.91) | 383.75 (75.64) | |
| Neutral/Happy (RT) | 324.58 (90.03) | 347.52 (55.07) |
Mean unadjusted scores of adolescents with Major Depressive Disorder and psychiatric-diagnosis free adolescents.
ANT, Attention Network Test; CPT, Continuous Performance Test; IGT, Iowa Gambling Task; MDD, Major Depressive Disorder; RT, reaction time.
a
CPT 2, 3, and 4 reflect increasing demands on digit span for recognition of identical number pairs.
b
Significant at p < .05 after adjustment for IQ Full-4 scores.