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. Author manuscript; available in PMC: 2015 Mar 31.
Published in final edited form as: Lancet. 2013 Jul 26;383(9911):69–82. doi: 10.1016/S0140-6736(13)60591-7

Figure 2. Pathological characteristics of the pancreas in type 1 diabetes.

Figure 2

(A) Islet infiltrate (ie, insulitis) seen in a patient with recent-onset type 1 diabetes. Immunohistochemistry shows the intra-islet presence of CD3-positive cells (brown) and glucagon-producing alpha cells (pink). Image courtesy of M Campbell Thompson, University of Florida, Gainsville, FL, USA. (B) Histological features of islets and (C) gross pathological characteristics of the pancreas associated with the natural history of type 1 diabetes (ie, preonset, onset, postonset).