Table 4. Genotype-phenotype decision descriptions for each model.

Models represent: 1. the two known DCM loci; 2. two known loci + 50% of the population is more susceptible to developing DCM; 3. two known DCM loci combined with a novel autosomal dominant DCM locus; 4. two known DCM loci combined with an autosomal recessive locus; 5. two known DCM loci combined with a an additional DCM locus that is additive and 6. two known DCM loci combined with an X-linked DCM locus.

Model	Genotype—phenotype decision description, in addition to the rules:
1.	DCM develops when both the PDK4 locus and Chr5 SNP have at least one DCM susceptibility allele.
2.	50% more susceptible only need to have a single DCM susceptibility allele at either locus to develop DCM while the 50% less susceptible to DCM require at least one DCM susceptibility allele at both loci to develop DCM.
3.	All individuals that have a susceptibility allele at the additional locus develop DCM. Those individuals with no susceptibility alleles at the additional locus need at least one DCM susceptibility allele at both of the other loci to develop DCM.
4.	All homozygous susceptible individuals at the additional locus develop DCM. For individuals that are heterozygous at the additional locus, DCM occurs when combined with another DCM susceptibility allele, while homozygous unsusceptible individuals need at least one DCM susceptibility allele at both of the other loci to develop DCM.
5.	All homozygous susceptible individuals at the additional locus develop DCM. Heterozygotes and homozygous unsusceptible individuals need at least one DCM susceptibility allele at both of the other loci to develop DCM.
6.	X linked susceptible DCM locus males can either possess a single unsusceptible X (XY) or a single susceptible x (xY), while females can be unsusceptible X homozygotes (XX), heterozygotes (Xx) or susceptible x homozygotes (xx). Unsusceptible X males (XY) are phenotypically identical to unsusceptible X homozygotes (XX) with these individuals requiring at least one DCM susceptibility allele at both of the other loci to develop DCM. All individuals that possess a susceptible X (xY and xx individuals) develop DCM in this model while heterozygotes (Xx) only require a single DCM susceptibility allele at one of the other loci to develop DCM.