Skip to main content
. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: Bioorg Med Chem. 2015 Feb 21;23(8):1849–1857. doi: 10.1016/j.bmc.2015.02.022

Table 6.

Cell-based assay comparison for compounds 1, 15e, 26c and NP counterpartsa

Compound A549
EC50 (nM)		 MDA-MB-231
EC50 		MRC-5
EC50
1 160 124 nM 53 nM
NP-1 52 117 nM 52 nM
15e 884 3.3 μM 2.3 μM
NP-15e 693 5.5 μM 1.8 μM
26c 32 50 nM 6.5 nM
NP-26c 6.5 724 nM 18 nM
a

Assays were carried out as triplicates