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. Author manuscript; available in PMC: 2015 Jun 4.
Published in final edited form as: Nature. 2014 Dec 4;516(7529):121–125. doi: 10.1038/nature13980

Extended Data Figure 8. Piezo1 expression and function in DRGs.

Extended Data Figure 8

a, in situ hybridization expression analysis of Piezo1 in DRG neurons relative to Piezo2. Robust expression of Piezo2 but not Piezo1 is observed, and this agrees with previously reported results using qPCR3. b, siRNA for Piezo1 in cultured DRG neurons does not affect the number of mechanically sensitive neurons or ratio of RA, IA or SA type currents (number of recorded neurons in each category indicated on top of bar graphs). Data from n = 3 independent preparations, n.s. by Student's t-test). Scale bar: 100 μm (a).