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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Int J Radiat Biol. 2014 Jun 25;90(9):753–761. doi: 10.3109/09553002.2014.922722

FIGURE 3.

FIGURE 3

Decrease in breathing interval during pneumonitis after 12.5 Gy whole thorax irradiation (WTI). For statistical comparisons, see Table I; differences are not identified in this graph for purposes of clarity in presentation. Note the decrease in breathing interval during pneumonitis at days 35, 42, 49 and 63 after 12.5 Gy WTI alone (p<0.05 at each of these time points, nadir at 42 days). Unirradiated rats and those given 30 Gy to the skin alone did not show changes in breathing intervals. Rats in the combined groups (12 Gy WTI+30 Gy skin) with or without captopril also exhibited decrease in breathing intervals that recovered by 84 days, with a nadir at 49 days.