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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Int J Radiat Biol. 2014 Jun 25;90(9):753–761. doi: 10.3109/09553002.2014.922722

FIGURE 4.

FIGURE 4

FIGURE 4

FIGURE 4

Histology and structure of the lung and heart at 42 days after 12.5 Gy irradiation (for details see Materials and Methods). Lungs and hearts were harvested from 5 groups (treatments i–v, see Materials and Methods). The lungs were weighed, fixed, sectioned and stained with anti-tryptase antibody. The hearts were dissected and the right ventricle as well as the left ventricle and septum were weighed separately. 4A. Representations of the mean±SEM of the number of mast cells/field in 5 experimental groups as labeled. N= 5 rats/group. Note the large increase in mast cells from lung sections of rats irradiated to the thorax only. B. Mean±SEM of wet weight of the lungs in each group. The lung weight doubled at 42 days after 12.5 Gy WTI. C. Depicts the ratio of the right ventricle:left ventricle+septum. Note the right ventricular hypertrophy in rats that received WTI, was mitigated by captopril.