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. Author manuscript; available in PMC: 2015 Mar 31.
Published in final edited form as: Gynecol Oncol. 2009 Jul 12;115(1):81–85. doi: 10.1016/j.ygyno.2009.06.021

Table 3.

Association of CA-125 levels during treatment with progress-free survival (PFS) and overall survival (OS).

PFS
OS
HR 95% C.I. P value HR 95% C.I. P value
Baseline CA125
  Log2(CA125) 1.10 1.02–1.18 0.009 1.09 1.01–1.17 0.032
  ≥35 versus < 35 U/ml 0.99 0.65–1.52 0.961 1.16 0.71–1.90 0.565
Pre-2nd cycle
  Log2(CA125) 1.24 1.15–1.34 <0.001 1.26 1.16–1.37 <0.001
  ≥35 versus < 35 U/ml 1.98 1.47–2.66 <0.001 2.88 2.01–4.16 <0.001
Pre-4th cycle
  Log2(CA125) 1.39 1.21–1.59 <0.001 1.46 1.26–1.68 <0.001
  ≥35 versus < 35 U/ml 1.80 1.27–2.56 0.001 1.94 1.31–2.85 <0.001
Pre-6th cycle
  Log2(CA125) 1.35 1.13–1.61 0.001 1.61 1.32–1.96 <0.001
  ≥35 versus < 35 U/ml 2.45 1.52–3.95 <0.003 2.78 1.66–4.65 <0.001

Hazard ratio (HR) estimated from Cox model adjusted for tumor residual, histology and type of chemotherapy.