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. Author manuscript; available in PMC: 2015 Mar 31.
Published in final edited form as: Addict Biol. 2014 Feb 9;20(2):285–296. doi: 10.1111/adb.12122

Figure 1.

Figure 1

Microinjection of the mGluR1/5 agonist DHPG into the accumbens core reinstated cocaine seeking. Total number of responses (mean ± SEM) on the active and inactive levers during the reinstatement test session following intra-accumbens core administration of vehicle (n = 7), 25.0 μM DHPG (n = 8) or 250 μM DHPG (n = 8). There was a significant increase in active lever responding in animals treated with 250 μM DHPG when compared with animals treated with vehicle (Bonferroni, *P < 0.05). No significant differences in responding on the inactive lever were found between treatments