Table II.
Clinical parameters of individuals in this pedigree.
| Pedigree ID no. | Gender/age (year) | Diagnosed at age (year) | BCVA OD/OS (2005) | BCVA OD/OS (2010) | Maximum IOP OD/OS mmHg | IOP (2005) OD/OS mmHg | IOP (2010) OD/OS mmHg | Optic Disc (C/D) OD/OS (2010) | VF Loss OD/OS | Therapy OD/OS | Diagnosis 2005 | Diagnosis 2010 | S341P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 096001 | M/82 | 0.6/0.5 | 0.4/0.25 | 17/17 | 17/17 | 16/16 | 0.3/0.4 | No/No | Normal | Normal | No | ||
| 096002 | F/82 | 65 | 0.5/0.5 | 0.3/0.2 | 17/22 | 17/18 | 17/22 | 0.4/0.5 | Yes/Yes | S/S | POAG | POAG | Yes |
| 096003 | M/61 | 55 | 1.0/0.8 | 0.6/0.6 | 52/50 | 45/40 | 30/30 | 0.6/0.7 | Yes/Yes | s/s | POAG | POAG | Yes |
| 096004 | F/60 | 1.0/1.0 | 1.0/0.8 | 17/17 | 17/17 | 17/17 | 0.3/0.4 | No/No | Normal | Normal | No | ||
| 096005 | M/32 | 25 | 1.2/CF | 1.0/CF | 48/NA | 48/NA | 17/33 | 0.8/0.9 | Yes/Yes | S/S | POAG | POAG | Yes |
| 099006 | F/55 | 50 | 1.0/1.0 | 1.0/1.0 | 21/24 | 17/20 | 21/24 | 0.6/0.6 | No/No | NMT | OHT | OHT | Yes |
| 096007 | F/49 | 1.2/1.2 | 1.0/1.0 | 17/16 | 17/17 | 17/16 | 0.3/0.3 | No/No | Normal | Normal | No | ||
| 096008 | F/44 | 1.0/1.2 | 1.0/1.0 | 17/18 | 17/18 | 17/18 | 0.5/0.4 | No/No | Normal | carrier | Yes | ||
| 096009 | M/41 | 1.0/1.2 | 1.0/1.2 | 17/21 | 17/21 | 17/21 | 0.4/0.4 | No/No | Normal | carrier | Yes | ||
| 096010 | F/40 | 1.0/1.2 | 1.0/1.2 | 17/17 | 16/16 | 16/16 | 0.3/0.3 | No/No | Normal | Normal | No | ||
| 096011 | F/14 | 1.0/1.0 | 1.0/1.2 | 16/16 | 16/16 | 16/16 | 0.3/0.3 | No/No | Normal | Normal | No | ||
| 096012 | M/20 | 1.0/1.0 | 1.0/1.0 | 17/17 | NA | NA | 0.3/0.3 | No/No | Normal | Normal | No |
M, male; F, female; BCVA, best-correct visual acuity; OD, right eye; OS, left eye; CF; count fingers; IOP, intraocular pressure; C/D, cup disc ratio; VF, visual field; NMT, no medical therapy; NA, unavailable; S, surgery; OHT, ocular hypertension.