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. 2015 Jan 6;78(3):413–420. doi: 10.1021/np5007907

Table 2. Antiplasmodial Activities for 1 and 2 Compared to Chloroquine against Chloroquine-Sensitive (D6) and -Resistant (Dd2 and 7G8) Strains of Plasmodium falciparum.

  IC50 (nM) against plasmodial strain
test compound D6 Dd2 7G8
companeramide A (1) 570 1000 1100
companeramide B (2) 220 230 700
chloroquine 5 80 71