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. 2015 Apr;145(4):257–259. doi: 10.1085/jgp.201511389

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© 2015 Adell

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Figure 1. — Schematic drawing of a 5-HT neuron showing exocytotic release from vesicles (red arrow) and the nonexocytotic release described by Mlinar et al. (2015) (blue arrow). Reuptake of 5-HT through SERT is depicted with a green arrow. SSRIs block SERT, thus inhibiting reuptake of 5-HT. Monoamine oxidase (MAO) enzyme is located in the external mitochondrial wall.