Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr;145(4):303–314. doi: 10.1085/jgp.201411292

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Ohrtman et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — Developmental changes in expression of full-length and truncated Ca_V1.1. (A) Western blots of membranes isolated from wild-type myotubes grown in culture for the indicated number of days (denoting plating as “Day 1”) and probed with the IIF7 monoclonal antibody, which recognizes both the full-length and truncated species. The leftmost lane illustrates membranes from dysgenic (Ca_V1.1-null) myotubes. Based on scanning densitometry, full-length Ca_V1.1 as a fraction of total (full-length plus truncated) is plotted as a function of developmental age in vitro (B) and in vivo (C). Error bars indicate SEM, and numbers of cultures or mice are indicated in parentheses. In B, myotubes from 4–5 d were grouped and plotted at day 4.5. In C, mice of 1–3, 5–9, 13–18, and 21–30 d, respectively, were grouped and plotted at time points corresponding to the average age of each group.