Table 5.
Associations between baseline concentrations of A) sTnI and B) hsTnI and presence or extent of epicardial CAD and coronary artery calcium score in patients undergoing CTA. Extremely low concentrations of TnI using both methods (but particularly hsTnI) were associated with less epicardial CAD and absence of coronary artery calcium.
A) sTnI | |||
---|---|---|---|
sTnI <LOD | sTnI LOD to 99th percentile | sTnI ≥99th percentile | |
Calcium score, median (IQR) | 0 [0–28] | 0.1 [0–3] | 213 [38–521] |
Any CAD | 55.6% | 50.0% | 90.0% |
Stenosis >50% | 18.8% | 16.7% | 80.0% |
Stenosis >70% | 12.5% | 0% | 70.0% |
B) hsTnI | |||
---|---|---|---|
hsTnI <LOD | hsTnI LOD to 99th percentile | hsTnI ≥99th percentile | |
Calcium score, median (IQR) | 0 [0-0] | 0 [0–29] | 111 [0.2–480] |
Any CAD | 11.1% | 58.3% | 83.3% |
Stenosis >50% | 0% | 19.4% | 75.0% |
Stenosis >70% | 0% | 13.0% | 58.3% |
LOD denotes: limit of detection; IQR denotes: interquartile range; CAD denotes: coronary artery disease