Table 1.

Demographic and clinical data of the PiB-negative and PiB-positive lvPPA patients

	PiB-negative	PiB-positive	P value
N	6	20	NA
Global PiB SUVR	1.2 (1.2–1.3)	2 (1.9–2.2)	<0.001
Gender (% female)	2 (33%)	8 (40%)	0.77
Education, years	17.5 (14.8–18)	14.5 (14–16.5)	0.30
Age at onset, years	63 (57.3–65.8)	62 (54–70)	0.90
Age at examination, years	66 (59.5–68)	63 (56–73)	0.90
Disease Duration, years	2 (2–2.8)	2 (1.9–3)	0.80
APOE e4 (%)	2 (33%)	11 (55%)	0.34
MMSE (/30)	26.5 (25.3–27.8)	25 (23.8–26.3)	0.34
WAB aphasia quotient (/100)	82.3 (75.6–88.7)	85.5 (81.3–88.3)	0.58
WAB information content (/10)	8 (8–8)	9 (7.8–10)	0.71
WAB repetition (/10)	7.5 (6.8–8.1)	8.4 (7.2–8.7)	0.30
WAB fluency (/10)	8 (6–9)	8 (8–9)	0.23
Boston Naming Test (/15)	11 (4.3–11.8)	8 (5.8–10.3)	0.50
Phonological error severity (0–3)	1 (1–1.8)	1 (1–1.3)	0.85
Pyramids and Palm Trees (/52)	47 (45.3–50.3)	47 (44–49)	0.65
Token Test (/22)	9 (7–13)	12 (8–16)	0.43
Action fluency	6 (4.3–8.5)	10.5 (5.8–14)	0.05
TMT A MOANS^a	9 (6.8–9.8)	6 (3–9.3)	0.23
DKEFS card sort^a	5 (1.8–6)	7 (3.5–9.0)	0.14
WMS-III VR % retention SS^a	9.5 (8–12.5)	8 (6–10.5)	0.32
VOSP cube analysis (/10)	10 (9.3–10)	7.5 (1.5–9)	0.05

Data shown as median (inter-quartile range). APOE= apolipoprotein E; DKEFS = Delis-Kaplan Executive Function System; MOANS = Mayo Older American Normative Studies; MMSE = Mini-Mental State Examination; TMT = Trail Making Test; VOSP = Visual Object and Space Perception Battery; WAB = Western Aphasia Battery; WMS-III VR % retention SS = Wechsler memory scale visual reproduction, percent retention, scaled score. P values were calculated using Wilcoxon Rank Sum tests for continuous data and Chi-squared tests for categorical data.

The MOANS, WMS-III VR % SS and DKEFS Card Sort are constructed to have a mean of 10 and standard deviation of 3 in cognitively healthy participants