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. 2015 Mar 31;10(3):e0122937. doi: 10.1371/journal.pone.0122937

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© 2015 Malik et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — A: Shown are the phases of individual neurospheres in SM expressing circadian rhythms plotted according to the first three peaks during imaging (left to right). Hour zero corresponds to the time when the forskolin treatment was removed and then projected over the next three days at 24-hour intervals. The mean vector of phases for individual spheres (arrow) had a significant magnitude (Rayleigh test, p<0.05) only during the first two cycles. B: Phases of spheres in B27 medium during the first circadian cycle and mean vector showing significant clustering.