Table 1. Measurements of Urinary Free BPA, BPA Glucuronide, and Total BPA in Infants and Young Children.
Authors and publication ear | Country | Population age | N | Laboratory method | LOD | Free BPA*(μg/L) | BPA-glucuronide* (μg/L) | Total BPA* (μg/L) | Detection Frequency: (Free/Total) |
---|---|---|---|---|---|---|---|---|---|
Volkel et al. 201134 | Germany (Munich) | 1 – 5 months | 47 | LC/MS-MS | 0.15 μg/L (LOQ = 0.45 μg/L) | All but 3 sample concentrations < LOQ | Not measured | Median < LOD | 9%/66% (per LOD); 3%/42% (per LOQ) |
Calafat et al. 200931 | U.S. (Boston) | Premature, ≤ 44 weeks corrected gestational age | 41 | LC/MS-MS | 0.4 μg/L | GM: 1.8, Median: 1.7 | Not measured | GM: 30.3, Median: 28.6 | 92%/100% |
Mendonca et al. 201235 | U.S. (Boston) | 2 – 15 months | 29 | LC/MS-MS | 0.4 μg/L | Mean: 0.5, GM < LOD, Median < LOD | Not measured | Mean: 6.0, GM: 2.3, Median: 1.8 | 28%/93% |
Nachman et al. 201336 | U.S. (Baltimore) | 1 – 6 weeks | 12 | LC/MS-MS | LOQ = 0.1 μg/L | < LOQ | Mean: 0.87, Median: 0.66 | Not meas. | 0%/100% |
Mean, geometric mean (GM) and median if reported. LOD = limit of detection; LOQ = limit of quantification.