Table 1. Characteristics from the included RCTs comparing endoscopic enucleation of the prostate with open prostatectomy.
| Reference | Publication year | Follow-up | Comparator | Trial size | Prostate | PSA | IPSS | Qmax | PVR | IIEF |
|---|---|---|---|---|---|---|---|---|---|---|
| mo | volume, mL | ng/mL | mL/s | mL | ||||||
| Kuntz et al. [7,34,35] | 2002, 2004, 2008 | 1,3,6,12,18,24,36,48,60 | HoLEP | 60 | 114.6±21.6 | NA | 22.1±3.3 | 3.8±3.6 | 280.0±273.0 | NA |
| OP | 60 | 113.0±19.2 | NA | 21.0±3.6 | 3.6±3.8 | 292.0±191.0 | NA | |||
| Naspro et al. [6] | 2006 | 1,3,12,24 | HoLEP | 41 | 113.3±35.3 | 6.3±3.5 | 20.1±5.8 | 7.8±3.4 | NA | 20.3±6.6 |
| OP | 39 | 124.2±38.5 | 7.0±4.3 | 21.6±3.2 | 8.3±2.4 | NA | 21.1±5.3 | |||
| Zhang et al. [21] | 2007 | 3 | HoLEP | 32 | 139.6±26.4 | NA | 27.4±5.5 | 6.1±2.9 | 197.8±33.6 | NA |
| OP | 28 | 157.2±35.1 | NA | 25.1±6.4 | 6.7±2.8 | 172.7±21.4 | NA | |||
| Geavlete et al. [25] | 2013 | 1,3,6,12,36 | BPEP | 70 | 132.6±50.0 a | 8.5±6.8 | 25.3±3.5 | 5.9±1.8 | 164.0±185.5 | NA |
| OP | 70 | 129.7±48.8 a | 8.4±6.9 | 25.6±3.8 | 5.7±1.8 | 168.0±183.0 | NA | |||
| Rao et al. [22] | 2014 | 1,3,6,12 | PKEP | 43 | 116.2±32.4 | 4.8±2.2 | 24.8±3.1 | 5.8±2.0 | 83.4±11.8 | 20.6±3.1 |
| OP | 40 | 110.2±32.1 | 4.5±2.1 | 24.5±3.6 | 5.9±2.3 | 81.4±15.7 | 20.3±3.4 | |||
| Chen et al. [24] | 2014 | 1,6,12,24,36,48,60,72 | PKEP | 80 | 110.0±20.7 | 2.9±0.9 | 25.6±3.3 | 4.0±2.2 | 240.0±170.4 | 22.0±3.0 |
| OP | 80 | 114.5±17.8 | 3.1±0.7 | 25.7±3.3 | 4.0±2.0 | 249.0±163.0 | 22.0±3.7 | |||
| Ou et al. [23] | 2013 | 3,12 | PKEP | 47 | 132.2±36.9 | 5.9±0.7 | 23.2±5.7 | 5.9±2.1 | 89.6±52.7 | NA |
| OP | 45 | 139.5±36.2 | 5.6±0.8 | 25.1±5.4 | 5.1±2.3 | 81.3±48.6 | NA |
aUnit: mL;
NA = not available; HoLEP = holmium laser enucleation of the prostate; BPEP = bipolar plasma vaporization enucleation of the prostate; PKEP = plasmakinetic enucleation of the prostate; IPSS = International Prostate Symptom Score; Qmax = maximum flow rate; QoL = quality of life; PVR = post-void residual urine volume; IIEF-5 = International Index of Erectile Function; mo = month.