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. Author manuscript; available in PMC: 2015 Mar 31.
Published in final edited form as: Immunol Res. 2014 May;58(0):249–258. doi: 10.1007/s12026-014-8514-3

Fig. 1.

Fig. 1

DBY seropositivity measured 3 months post-HCT predicts cGVHD development. a Heatmap representation of IgG specific for H-Y antigen DBY in 69 seropositive F → M patients. 67 seronegative patients are not shown. Overall, DBY seropositivity at 3 months was 19 and 51 % at any time point following HCT. Each row represents the results of a separate patient with the time of serum collection shown on the x-axis. The threshold for seropositivity was determined measuring 60 normal male donors. The heat reflects relative DBY antibody level relative to this threshold. Importantly, patient death is denoted by black, and missing samples are white. b The competing incidence of cGVHD development is greater in DBY seropositive patients than in DBY seronegative patients (p < 0.01)