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Blunted liver regeneration in Prl-1 male mutant mice detected by phosphorylated histone 3 (PH3) staining. A: liver sections were collected at 40 h posthepatectomy and stained for PH3, a marker of M phase. The number of PH3-positive cells was significantly reduced in Prl-1 mutants. B: quantification of PH3-positive cells at 40 h posthepatectomy (n = 5). Data are means ± SE. **P < 0.01 vs. controls.
