Figure 4. PKM2 expression is increased in the failing human heart.
(A) Uncut (U) or PstI digested (P) PKM cDNA amplicon of heart muscle samples from non-failing and failing hearts before (Implant) and after (Explant) mechanical unloading. (B) PKM2 expression in paired human samples before (implant) and after (explant) mechanical unloading. (C) Western blot of O-GlcNAcylated proteins in non-failing and failing hearts. Data are ±SEM of 6–11 human samples. *P < 0.05 and **P < 0.01.