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Published in final edited form as: Pharmacol Ther. 2014 Dec 27;149:150–190. doi: 10.1016/j.pharmthera.2014.12.004
© 2014 The Authors. Published by Elsevier Inc.
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).