Table 1.
Zone | Regimen | Peptide Vaccine | Adjuvant Preparation | Dose of TLR agonists |
---|---|---|---|---|
Z 1 | d 1 | LPV7 + tet | IFA | — |
Z 1 | d 2 | LPV7 + tet | PolyICLC | 1 mg |
Z 1 | d 3 | LPV7 + tet | Resquimod | 112.5 mcg |
Z 2 | d 4 | LPV7 + tet | IFA + PolyICLC | 1 mg / 112.5 mcg |
Z 2 | d 5 | LPV7 + tet | IFA + Resquimod | 1 mg |
Z 2 | d 6 | LPV7 + tet | PolyICLC + Resquimod | 112.5 mcg |
Z 3 | d 7 | LPV7 + tet | IFA + PolyICLC + Resquimod | 1 mg / 112.5 mcg |