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The number of neurons and glia (mean±SEM) in the upper and lower layers of the mPFC. In the upper layers, no change in the number of neurons was found after male or female gonadectomy (a), but there was a significant difference in the number of glia between OVX and sham control females (b). In the lower layers, the number of both neurons (c) and glia (d) were significantly different between OVX and sham control females. GDX males were not affected by castration. *p<.05; **p<.01
