Table 1.
Baseline and endocrine parameters of women with PCOS and control women
| Casesa | Controlsa | P b | |
|---|---|---|---|
| Age (years)c | 28.3 ± 6.1 | 26.9 ± 7.7 | 0.082 |
| BMI (kg/m2)c | 29.9 ± 6.3 | 25.7 ± 5.3 | 2.3 × 10−6 |
| Waist/hip ratio (WHR)c | 0.85 ± 0.12 | 0.83 ± 0.12 | 0.286 |
| LH (IU/L)d | 6.5 (0.8–66.6) | 5.4 (0.4–56.3) | 0.063 |
| FSH (IU/L)d | 5.3 (0.5–16.8) | 5.3 (0.4–15.4) | 0.568 |
| LH/FSHd | 1.3 (0.05–6.12) | 1.0 (0.2–10.9) | 0.060 |
| TSH (μIU/ml)c | 2.7 ± 2.1 | 1.7 ± 0.9 | 0.006 |
| Menarche (years)c | 12.4 ± 1.4 | 12.6 ± 1.4 | 0.247 |
| Total testosterone (nmol/L)c | 1.8 ± 1.0 | 1.7 ± 1.1 | 0.583 |
| Free testosterone (pmol/L) | 25.2 (3.3–92.4) | 18.4 (0.7–49.2) | 0.009 |
| Bioavailable testosterone (pmol/L)d | 684.0 (149.0–2020.0) | 469 (95.9–1480.0) | 0.004 |
| Free androgen index (FAI)d | 5.1 (0.7–320.8) | 3.1 (0.3–151.7) | 0.015 |
| SHBG (nmol/L)d | 20.1 (12.9–185.3) | 57.7 (12.6–189.8) | 1.4 × 10−6 |
| Fasting insulind | 10.2 (1.6–99.4) | 7.2 (1.7–22.1) | 2.6 × 10−4 |
| HOMA-IRc | 3.8 ± 2.7 | 1.9 ± 0.9 | 1.8 × 10−4 |
| QUICKIc | 0.58 ± 0.12 | 0.65 ± 0.11 | 0.001 |
| Total cholesterol (mmol/L)c | 4.8 ± 1.3 | 4.7 ± 1.0 | 0.804 |
| HDL-cholesterol (mmol/L)c | 1.3 ± 0.6 | 1.4 ± 0.5 | 0.498 |
| LDL-cholesterol (mmol/L)c | 2.7 ± 0.9 | 2.6 ± 0.6 | 0.591 |
| Triglycerides (mmol/L)c | 1.5 ± 1.0 | 1.1 ± 0.8 | 0.135 |
aA total of 203 PCOS cases and 211 control women were included
bStudent’s t-test (variables with normal distribution), Mann–Whitney U-test (variables that were not normally distributed)
cMean ± SD
dPercent of total within each group/subgroup