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. 2015 Feb 4;32(4):607–614. doi: 10.1007/s10815-015-0427-0

Table 3.

LHCGR and FSHR genotype frequencies

1 / 1 1 / 2 2 / 2
Locus SNP Cases Controls P a Cases Controls aORb (95 % CI) Cases Controls aOR (95 % CI)
LHCGR rs2293275 93 (0.46)c 102 (0.48) 0.57 81 (0.40) 74 (0.35) 1.20 (0.79–1.83) 29 (0.14) 35 (0.17) 0.91 (0.52–1.60)
rs7371084 184 (0.91) 172 (0.82) 0.023 17 (0.08) 37 (0.18) 0.44 (0.24–0.80) 2 (0.01) 2 (0.01) 0.95 (0.13–6.82)
rs4953616 70 (0.34) 103 (0.49) 0.007 91 (0.45) 81 (0.38) 1.66 (1.08–2.56) 42 (0.21) 27 (0.13) 2.30 (1.30–4.08)
rs4597581 130 (0.64) 132 (0.63) 0.86 61 (0.30) 68 (0.32) 0.91 (0.60–1.39) 12 (0.06) 11 (0.05) 1.13 (0.48–2.64)
rs13405728 168 (0.83) 170 (0.81) 0.46 35 (0.17) 40 (0.19) 0.89 (0.53–1.47) 0 (0.00) 1 (0.005) 0.00 (0.00–NA)
rs4073366 169 (0.83) 183 (0.87) 0.60 32 (0.16) 27 (0.13) 1.25 (0.72–2.18) 2 (0.01) 1 (0.005) 2.18 (0.20–24.22)
FSHR rs1007541 170 (0.84) 177 (0.84) 1.00 31 (0.12) 32 (0.15) 0.98 (0.57–1.69) 2 (0.01) 2 (0.01) 1.05 (0.06–16.88)
rs11692782 78 (0.38) 60 (0.28) 8.0 × 10−4 79 (0.39) 121 (0.57) 0.50 (0.32–0.78) 46 (0.23) 30 (0.14) 1.17 (0.66–2.07)
rs2055571 75 (0.37) 69 (0.33) 0.20 80 (0.39) 102 (0.48) 0.72 (0.46–1.13) 48 (0.24) 40 (0.19) 1.09 (0.64–1.88)
rs1394205 130 (0.64) 115 (0.55) 0.08 61 (0.30) 86 (0.41) 0.63 (0.41–0.96) 12 (0.06) 10 (0.05) 1.08 (0.45–2.59)
rs6166 64 (0.32) 52 (0.26) 0.31 92 (0.45) 107 (0.51) 0.70 (0.44–1.12) 47 (0.23) 52 (0.26) 0.74 (0.43–1.27)

Genotypes were coded as per “1” = major allele, “2” = minor allele

a2-way ANOVA

baOR = adjusted OR; covariates that were controlled for were BMI, TSH, FT, BT, FAI, SHBG, and fasting insulin

cNumber of subjects (frequency)