Table 4.
Distribution of FSHR and LHCGR variants in women with PCOS and control women according to obesity
| Non-obese (BMI <30 kg/m2) | Obese (BMI ≥30 kg/m2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gene | SNP | Genotype | Cases | Controls | χ2 | P a | Cases | Controls | χ2 | P a |
| FSHR | rs11692782 | A/A | 26 (41.3)b | 26 (24.5) | 9.30 | 0.010 | 4 (36.4) | 4 (20.0) | 6.48 | 0.039 |
| A/T | 24 (38.1) | 66 (62.3) | 25 (37.9) | 14 (70.0) | ||||||
| T/T | 13 (20.6) | 14 (13.2) | 17 (25.8) | 2 (10.0) | ||||||
| LHCGR | rs4953616 | T/T | 21 (33.9) | 50 (47.2) | 5.00 | 0.082 | 20 (31.7) | 11 (55.0) | 3.59 | 0.166 |
| T/C | 26 (41.9) | 43 (40.6) | 31 (49.2) | 6 (30.0) | ||||||
| C/C | 15 (24.2) | 13 (12.3) | 27 (21.6) | 16 (12.7) | ||||||
| LHCGR | rs7371084 | T/T | 62 (96.9) | 85 (80.2) | 9.50 | 0.002 | 57 (89.1) | 17 (85.0) | 0.24 | 0.695 |
| T/C | 2 (3.1) | 21 (19.8) | 7 (10.9) | 3 (15.0) | ||||||
a2-way ANOVA
bNumber of subjects (frequency)