Table 2.
Mean erectile function, satisfaction, and penile pain scores at 12 (M12) and 24 months (M24) after bilateral nerve-sparing radical prostatectomy
| N = 75 | M12 | M24 | P value |
|---|---|---|---|
| Number of IAI/week | 1.88 ± 0.86 | 1.61 ± 0.69 | 0.15 |
| Dose injected (μg) | 8.97 ± 5.20 | 10.18 ± 6.13 | 0.072 |
| Pain at erection (0–10) | 2.92 ± 2.70 | 2.52 ± 2.35 | 0.66 |
| IIEF-EF with treatment | 19.60 ± 9.80 | 18.07 ± 10.44 | 0.92 |
| IIEF-EF without treatment | 4.63 ± 2.93 | 4.92 ± 4.15 | 0.28 |
| IIEF-OF with treatment by IAI | 5.18 ± 3.42 | 5.58 ± 3.42 | 0.27 |
| IIEF-SD | 6.05 ± 2.32 | 5.93 ± 2.06 | 0.74 |
| IIEF-IS | 7.18 ± 4.11 | 6.51 ± 4.23 | 0.69 |
| IIEF-OS | 5.48 ± 2.70 | 5.62 ± 2.56 | 0.34 |
| EHS with treatment by IAI | 2.97 ± 1.30 | 2.57 ± 1.30 | 0.47 |
| EHS without treatment by IAI | 0.67 ± 1.11 | 0.76 ± 0.10 | 0.14 |
| Satisfaction with treatment by IAI, n (%) | 0.013 | ||
| Satisfied | |||
| Very satisfied | 16 (21.3%) | 9 (12%) | |
| Moderately satisfied | 34 (45.3%) | 26 (34.7%) | |
| Not satisfied | |||
| Neither satisfied nor dissatisfied | 9 (12%) | 13 (17.3%) | |
| Moderately dissatisfied | 8 (10.7%) | 14 (18.6%) | |
| Very dissatisfied | 8 (10.7%) | 13 (17.3%) | |
| GAQ | |||
| GAQ1, Yes, n (%) | 65 (86.7%) | 57 (76%) | 0.093 |
| GAQ2, Yes, n (%) | 53 (70.7%) | 46 (61.3%) | 0.22 |
| Sexual bother (UCLA-PCI) | 37.14 ± 21.45 | 37.54 ± 19.67 | 0.759 |
| Report of nocturnal erection (UCLA-PCI) | 0.002 | ||
| Never | 60 (80.5%) | 49 (64.9%) | |
| Less than 25% | 7 (9.8%) | 24 (31.6%) | |
| Less than 50% | 4 (4.9%) | 0 (0%) | |
| More than 50% | 4 (4.9%) | 1 (1.8%) | |
| More than 75% | 0 (0%) | 1 (1.8%) |
Results are means (±standard deviation). Significant values are in bold
IIEF = International Index of Erectile Function; IIEF domains: EF = erectile function; OF = orgasmic function; SD = sexual drive; IS = intercourse satisfaction; OS = overall satisfaction; EHS = erection hardness score; IAI = intracavernous alprostadil injection