Table 1.
Cell line | Genetic subtype | ER | PR | Her2 | TP53 | N-cadherin | Shape cluster |
---|---|---|---|---|---|---|---|
hs578T | BaB | − | [−] | − | +M | ++ | B |
MCF10A (complete medium) | BaB | − | [−] | − | +/−WT | ++ | L/B |
MCF10A (base medium) | BaB | − | [−] | − | +/−WT | ++ | L2 |
MDAMB157 | BaB | − | [−] | − | − | ++ | B |
MDAMB231 | BaB | − | [−] | − | ++M | − | B |
SUM149 | BaB | [−] | [−] | − | [+] | + | B |
SUM159 | BaB | [−] | [−] | − | [−] | ++ | L/B |
HCC1143 | BaA | − | [−] | − | ++M | ++ | B |
HCC1954 | BaA | − | [−] | + | [+/−] | − | L1 |
HCC70 | BaA | − | [−] | − | ++M | − | L2 |
AU565 | Lu | − | [−] | + | +WT | − | L2 |
BT474 | Lu | + | − | + | + | − | L2 |
CAMA1 | Lu | + | [−] | − | + | − | L2 |
MCF7 | Lu | + | [+] | − | +/−WT | − | L1 |
MDAMB453 | Lu | − | [−] | − | −WT | − | L2 |
SKBR3 | Lu | − | [−] | + | + | − | B |
T47D | Lu | + | [+] | − | ++M | − | L1 |
ZR75.1 | Lu | + | [−] | − | − | − | L2 |
JIMT1 | − | [−] | + | ++ | − | L1 |
Gene cluster: Lu = luminal, BaA = Basal A, BaB = Basal B. ER/PR/HER2/TP53 status: +/− from protein and mRNA expression; [−] inferred from mRNA expression; M = mutant, WT = wild-type (Neve et al, 2006). N-cadherin status: +/− from mRNA expression and immunofluorescence (Supplementary Fig S1B). Shape clusters assigned from hierarchical clustering shown in Fig1D.