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. 2015 Apr 1;35(13):5247–5259. doi: 10.1523/JNEUROSCI.3494-14.2015

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Copyright © 2015 the authors 0270-6474/15/355247-13$15.00/0

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Figure 1. — SNI evokes sensory and depressive symptoms of chronic pain. A, B, SNI-treated rats developed mechanical and cold allodynia, compared with sham-treated rats. Two-way ANOVA with repeated measures and Bonferroni's post-test, n = 6, p < 0.0001. C, SNI-treated rats developed decreased preference for sucrose in the SPT, a test of anhedonia. Student's t test, n = 8, p < 0.001. D, SNI-treated rats developed decreased motivation or behavioral despair, as indicated by prolonged immobility on the FST. Student's t test, n = 4, p < 0.05. Error bars show mean and SEM.