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LRRK2 KO decreases cleaved caspase-3 expression at the Tat injection site. A–F, IHC for NeuN (red), cleaved caspase-3 (green), and DAPI (blue) in saline control animals (A, 10×; D, 10×), Tat-treated WT mice (B, 10×; C, 60×), and Tat-treated KO mice (E, 10×; F, 60×). G, LRRK2 KO significantly decreases cleaved caspase-3 expression in Tat-treated animals (*p < 0.05, one-way ANOVA with Newman–Keuls post hoc test). Scale bars: A, B, D, E, 60 μm; C, F, 11 μm.
