Skip to main content
. 2015 Apr 1;35(13):5317–5329. doi: 10.1523/JNEUROSCI.0122-15.2015

Figure 4.

Figure 4.

Prospective VGLUT3 lineage neurons acquire molecular features of MrgprD+ nociceptors in Zfp521 CKO mice. A–I, Double staining of Tomato with indicated mRNAs detected by ISH on sections through P30 lumbar DRG of control littermate mice (ROSA26Tomato/+;Vglut3Cre/+) and Zfp521 CKO mice (Zfp521F/F;ROSA26Tomato/+;Vglut3Cre/+). Arrows indicate derepression of gene expression in CKO mice (B–E). Arrowheads in E indicate low P2X3 expression in VGLUT3-Tomato+ neurons in control mice. F–I indicate no derepression of these markers. J, Summary of dual functions of Zfp521. Scale bars, 50 μm.