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. 2015 Mar 3;43(6):3056–3067. doi: 10.1093/nar/gkv144

Figure 1.

Figure 1.

A large fraction of genomic cohesin positions are tissue-specific. (A) Number of cohesin SMC1 and SA1 positions in cerebral cortex and pancreas from 10 week-old mice obtained by ChIP-seq. Two replicates corresponding to independent experiments containing tissue from at least three individuals were performed. (B) Venn diagrams showing the overlap between SMC1 and SA1 positions in each tissue and between tissues. For cohesin and CTCF peaks (see Supplementary Figure S1), overlap is defined as reciprocal coincidence over at least 50% of peak length. (C) UCSC genome browser images illustrating cortex-specific (upper panel) and pancreas-specific (lower panel) cohesin positions located in chromosomes 11 and 15, respectively. The values for ChIP-seq data (y-axis) are normalized to input.