Table 2.
Nomenclatures and definitions used in hepatitis B virus infection
| Markers | Chronic inactive carrier | HBeAg positive CHB | HBeAg negative CHB | “Resolved hepatitis B” |
| HBsAg | + | + | + | - |
| HBeAg | - | + | - | - |
| Anti-HBe | + | - | +/- | +/- |
| Anti-HBs | + | - | +/- | +/- |
| Anti-HBc | + | +/- | + | +/- |
| ALT | - | +/- | + | - |
| Serum HBV-DNA | Undetectable/< 2000 IU/mL | Persistent/intermittent ↑ (> 20000 IU/mL) | Persistent/intermittent ↑ (> 2000 UI/mL) | Detectable or undetectable |
| Liver injury | +/- | Moderate/severe CHB | Minimal to severe CHB | - |
| Necroinflammation | No (> 90%) | Yes (> 90%) | No (> 90%) | No |
CHB: Chronic hepatitis B; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; anti-HBe: Antibodies to hepatitis B e antigen; anti-HBs: Antibodies to hepatitis B surface antigen; anti-HBc: Antibodies to hepatitis B core antigen; ALT: Alanine aminotransferase.