Table 2.

2005 World Congress of Gastroenterology diagnostic and supportive criteria for cirrhotic cardiomyopathy[1]

A working definition of cirrhotic cardiomyopathy

A cardiac dysfunction in patients with cirrhosis characterised by impaired contractile responsiveness to stress and/or altered diastolic relaxation with electrophysiological abnormalities in the absence of other known cardiac disease

Diagnostic criteria

Systolic dysfunction

Blunted increase in cardiac output on exercise, volume challenge or pharmacological stimuli

Resting LVEF < 55%

Diastolic dysfunction

E/A ratio < 1 (age-corrected)

Prolonged deceleration time (> 200 ms)

Prolonged isovolumetric relaxation time (> 80 ms)

Supportive criteria

Electrophysiological abnormalities

Abnormal chronotropic response

Electromechanical uncoupling

Prolonged QTc interval

Enlarged left atrium

Increased myocardial mass

Increased BNP (brain natriuretic peptide) and pro-BNP

Increased troponinI

BNP: B-type natriuretic peptide; LVEF: Left ventricular ejection fraction.