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Dose-response effects of dalargin-coated nanoparticles. Response determined 15 min after intravenous injection (DAL/NP, 2.5–10 mg/kg) at either 08:00 or 20:00; lights on from 07:00 to 19:00. Shown are mean values ± SEM of the maximal possible effect (% MPE. Adapted with permission from [13]. Copyright 1999 Informa Healthcare).
