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. 2015 Feb 12;7(1):353–381. doi: 10.3390/cancers7010353

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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The total absorbed dose along a proton SOBP is shown, by separating contributions coming from primary protons and from secondary fragments (A < 5). Adapted from Paganetti [114].