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. 2015 Mar 18;7(1):481–502. doi: 10.3390/cancers7010481

Figure 2.

Figure 2

Survival fraction of A549 cells (A,C) and EC (B,D) exposed to alpha particles (A,B) or to proton beam (C,D) in mono- (hatched columns) or co-culture configurations (filled columns). Survival fraction was calculated using conventional clonogenic assays. Monoculture controls were set to one and all other configurations were normalized with monoculture controls. Results are presented as means ± 1 S.D. (A, B, C: three independent experiments with n = 3, D: two independent experiments with n = 2). * = irradiated cells. One-way ANOVA and Tukey’s multiple comparison post-test: ++ p < 0.01; +++ p < 0.001. Comparison with monoculture controls: $$ p < 0.01; $$$ p < 0.001; comparison with co-culture controls: ## p < 0.01; ### p < 0.001. ns: nonsignificant.