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. 2015 Mar 18;7(1):481–502. doi: 10.3390/cancers7010481

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Effects of alpha particle (1 Gy) irradiation on the mRNA expression of FAS, CCL2, CCL5, CSF1, IL8, IL1B, CXCL10, FGF2, PDGFB and p21 in A549 cells in mono- (hatched columns) or in co-culture (filled columns) configurations. Total RNA was extracted 24 h after irradiation and mRNA levels were quantified by RT-qPCR. Results are presented in induction fold as means ± 1 S.D. (n = 3) by comparison with non-irradiated cells in monoculture (CTL A549). * = irradiated cells. Repeated measures one-way ANOVA and Tukey post-test: + p < 0.05; +++ p < 0.001. Comparison with monoculture controls: $ p < 0.05; $$ p < 0.01; $$$ p < 0.001; comparison with co-culture controls: # p < 0.05; ### p < 0.001. ns: nonsignificant.